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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/VU 0240551/3888/10/10 mg
产品编号:3888/10
市  场 价:¥3380.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$169.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/VU 0240551/3888/10/10 mg
商品介绍
Description:KCC2inhibitor
ChemicalName:N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitoroftheneuronalK-Clcotransporter,KCC2(IC50=560nMforK+uptakeassayinKCC2-overexpressingcells).ExhibitsselectivityovertheNa-K-2Clcotransporter,NKCCl.AlsoinhibitshERGandL-typeCa2+channels.

TechnicalData

M.Wt342.43
FormulaC16H14N4OS2
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber893990-34-6
PubChemID7211972
InChIKeyWJRWSLORVIHRNX-UHFFFAOYSA-N
SmilesO=C(NC3=NC(C)=CS3)CSC(C=C2)=NN=C2C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.24100
ethanol8.5625

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight342.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.92mL14.6mL29.2mL
5mM0.58mL2.92mL5.84mL
10mM0.29mL1.46mL2.92mL
50mM0.06mL0.29mL0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet