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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/VER 155008/3803/10/10 mg
产品编号:3803/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>白蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/VER 155008/3803/10/10 mg
商品介绍
Description:Hsp70inhibitor
ChemicalName:5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Noveladenosine-derivedinhibitorofHeatShockProtein70(Hsp70)(IC50=0.5μM).Inhibitscellproliferationofmultiplehumantumorcelllinesinvitro.AlsobindsHsc70andGrp78;displaysselectivityagainstHsp90β(IC50>200μMforHsp90β).

CompoundLibraries

VER155008isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt556.4
FormulaC25H23Cl2N7O4
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1134156-31-2
PubChemID25195348
InChIKeyZXGGCBQORXDVTE-UMCMBGNQSA-N
SmilesNC1=NC=NC2=C1N=C(NCC5=CC=C(Cl)C(Cl)=C5)N2[C@@H]3O[C@H](COCC4=CC=C(C#N)C=C4)[C@@H](O)[C@H]3O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO55.64100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight556.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.8mL8.99mL17.97mL
5mM0.36mL1.8mL3.59mL
10mM0.18mL0.9mL1.8mL
50mM0.04mL0.18mL0.36mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet