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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/UPF 648/4926/10/10 mg
产品编号:4926/10
市  场 价:¥5780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$289.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/UPF 648/4926/10/10 mg
商品介绍
Description:Potentkynurenine3-monooxygenase(KMO)inhibitor
ChemicalName:(1S,2S)-2-(3,4-Dichlorobenzoyl)cyclopropanecarboxylicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentkynurenine3-monooxygenase(kynurenine3-hydroxylase;KMO)inhibitor(IC50=20nM).Increaseskynurenicacidlevels,anddecreases3-HKandQUINlevelsincerebrumandliverofneonatalrodents.NeuroprotectiveinaDrosophilamodelofHuntington'sdisease.

TechnicalData

M.Wt259.09
FormulaC11H8Cl2O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber213400-34-1
PubChemID9859947
InChIKeyZBRKMOHDGFGXLN-BQBZGAKWSA-N
Smiles[H][C@]1([C@@H]([C@](O)=O)C1)C(C2=CC=C(Cl)C(Cl)=C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
ethanol25.91100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight259.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.86mL19.3mL38.6mL
5mM0.77mL3.86mL7.72mL
10mM0.39mL1.93mL3.86mL
50mM0.08mL0.39mL0.77mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet