Selectivepoly(ADP-ribose)polymerase(PARP)2inhibitor(IC50valuesare0.3and8.0μMforPARP-2andPARP-1respectively).
UPF1069isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 279.29 |
Formula | C17H13NO3 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 1048371-03-4 |
PubChemID | 25015515 |
InChIKey | JJWMRRNGWSITSQ-UHFFFAOYSA-N |
Smiles | O=C2NC=CC1=C(OCC(C3=CC=CC=C3)=O)C=CC=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 27.93 | 100 |
Thefollowingdataisbasedontheproductmolecularweight279.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.58mL | 17.9mL | 35.81mL |
5mM | 0.72mL | 3.58mL | 7.16mL |
10mM | 0.36mL | 1.79mL | 3.58mL |
50mM | 0.07mL | 0.36mL | 0.72mL |