Methyl-lysine(Kme)readerdomaininhibitor;bindstotheMBTdomainoftheL3MBTL1protein(Kd=3.9μM).SelectivelyinhibitstheL3MBTL13XMBT-H4K20me1interactioninapeptidepulldownassay.
UNC926hydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 373.72 |
Formula | C16H21BrN2O.HCl |
Storage | DesiccateatRT |
Purity | ≥99%(HPLC) |
CASNumber | 1184136-10-4 |
PubChemID | 90488947 |
InChIKey | DPPMBBHOXQOMJI-UHFFFAOYSA-N |
Smiles | BrC1=CC=CC(C(N2CCC(N3CCCC3)CC2)=O)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 37.37 | 100 | |
ethanol | 37.37 | 100 | |
water | 37.37 | 100 |
Thefollowingdataisbasedontheproductmolecularweight373.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.68mL | 13.38mL | 26.76mL |
5mM | 0.54mL | 2.68mL | 5.35mL |
10mM | 0.27mL | 1.34mL | 2.68mL |
50mM | 0.05mL | 0.27mL | 0.54mL |