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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/UFP-101/1552/1/1 mg
产品编号:1552/1
市  场 价:¥6180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$309.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/UFP-101/1552/1/1 mg
商品介绍
Description:Potent,selectivesilentantagoNISTforNOP
AlternativeNames:[Nphe1,Arg14,Lys15]Nociceptin-NH2
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveandcompetitivesilentantagonistfortheNOPopioidreceptor.BindstoNOPwithhighaffinity(pKi=10.24)anddisplays>3000-foldselectivityoverδ,μandκopioidreceptors.Antinociceptiveandopposestheactionofnociceptininvivo.

TechnicalData

M.Wt1908.19
FormulaC82H138N32O21
SequenceGGGFTGARKSARKRKNQ

(Modifications:Gly-1=N-(Bn)Gly,Gln-17=C-terminalamide)

StorageDesiccateat-20°C
CASNumber849024-68-6
PubChemID16152632
InChIKeyDOLKPWDXAQZKNJ-LGCGZHPXSA-N
SmilesC[C@@H](O)[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)CNCC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1908.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.52mL2.62mL5.24mL
5mM0.1mL0.52mL1.05mL
10mM0.05mL0.26mL0.52mL
50mM0.01mL0.05mL0.1mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet