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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/UCPH 101/3490/10/10 mg
产品编号:3490/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/UCPH 101/3490/10/10 mg
商品介绍
Description:Selectivenon-substrateEAAT1inhibitor
ChemicalName:2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivenon-substrateinhibitorofEAAT1(IC50valuesare660,>300000and>300000nMforEAAT1,EAAT2andEAAT3respectively).AlsodemonstratesnosignificantinhibitionatEAAT4orEAAT5inapatch-clampelectrophysiologyassay(atfinalconcentrationupto10μM).

TechnicalData

M.Wt422.48
FormulaC27H22N2O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1118460-77-7
PubChemID25223366
InChIKeyYBMGNDPBARCLFT-UHFFFAOYSA-N
SmilesNC2=C(C#N)C(C3=CC=C(OC)C=C3)C1=C(O2)CC(C4=C(C=CC=C5)C5=CC=C4)CC1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.5625

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.83mL23.67mL
5mM0.47mL2.37mL4.73mL
10mM0.24mL1.18mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet