PotentendocannABInoidtransportinhibitor.IC50valuesare0.8and30μMforinhibitionoftheanandamidetransporterandFAAHrespectively.Kivaluesare4700,67and>5000nMforCB1,CB2andVR1receptorsrespectively.Potentiateshypokineticandantinociceptiveeffectsofanandamideinvivo.
| M.Wt | 383.57 |
| Formula | C25H37NO2 |
| Storage | Desiccateat-20°C |
| CASNumber | 390824-20-1 |
| PubChemID | 10199993 |
| InChIKey | FZNNBSHTNRBBBD-DOFZRALJSA-N |
| Smiles | O=C(NCC1=COC=C1)CCCC=C/CC=C/C/C=CC/C=CCCCCC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 38.36 | 100 | |
| ethanol | 38.36 | 100 |
Thefollowingdataisbasedontheproductmolecularweight383.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.61mL | 13.04mL | 26.07mL |
| 5mM | 0.52mL | 2.61mL | 5.21mL |
| 10mM | 0.26mL | 1.3mL | 2.61mL |
| 50mM | 0.05mL | 0.26mL | 0.52mL |



