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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/U 73122/1268/50/50 mg
产品编号:1268/50
市  场 价:¥11580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$579.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/U 73122/1268/50/50 mg
商品介绍
Description:PhospholipaseCinhibitor
ChemicalName:1-[6-[[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PhospholipaseCinhibitor.InhibitsagoNIST-inducedplateletaggregationwithIC50valuesof1-5μM.Potentlyinhibitshumanpolymorphonuclearneutrophiladhesiononbiologicalsurfaces(IC50<50nM)andexhibitsantinociceptiveactivityinvivo.AlsoactivatesTRPM4andinhibitsTRPM3channels.NegativecontrolU73343(Cat.No.4133)alsoavailable.

LicensingInformation

SoldwiththepermissionofPharmacia

TechnicalData

M.Wt464.65
FormulaC29H40N2O3
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber112648-68-7
PubChemID104794
InChIKeyLUFAORPFSVMJIW-ZRJUGLEFSA-N
Smiles[H][C@]23[C@@]([C@]([H])(CC[C@@H]4NCCCCCCN5C(C=CC5=O)=O)[C@]4(C)CC3)([H])CCC1=CC(OC)=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

Solubility

PleaserefertothesesolubilityguidelinesforU73122(Cat.No.1268).

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight464.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.15mL10.76mL21.52mL
5mM0.43mL2.15mL4.3mL
10mM0.22mL1.08mL2.15mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet