Potentcarbonicanhydrase(CA)inhibitor(Kivaluesare4.5,45.1,5080and9640nMforCAXII,CAIX,CAIandCAIIrespectivelyinMDA-MB-231cells).Inhibitstumormetastasisintherat4T1metastasismodel.
U104isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 309.32 |
Formula | C13H12FN3O3S |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 178606-66-1 |
PubChemID | 310360 |
InChIKey | YJQZNWPYLCNRLP-UHFFFAOYSA-N |
Smiles | FC1=CC=C(NC(NC2=CC=C(S(=O)(N)=O)C=C2)=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.93 | 100 |
Thefollowingdataisbasedontheproductmolecularweight309.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.23mL | 16.16mL | 32.33mL |
5mM | 0.65mL | 3.23mL | 6.47mL |
10mM | 0.32mL | 1.62mL | 3.23mL |
50mM | 0.06mL | 0.32mL | 0.65mL |