Epidermalgrowthfactorreceptor(EGFR)kinaseinhibitor(IC50=0.86μM).Slightlylessactivethanthe(-)enantiomer(Cat.No.0578).
| M.Wt | 308.34 |
| Formula | C18H16N2O3 |
| Storage | Desiccateat+4°C |
| CASNumber | 133550-37-5 |
| PubChemID | 5328769 |
| InChIKey | UMGQVUWXNOJOSJ-DGGAMASNSA-N |
| Smiles | OC1=C(O)C=CC(C=C(C(N[C@@H](C)C2=CC=CC=C2)=O)/C#N)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 9.25 | 30 |
Thefollowingdataisbasedontheproductmolecularweight308.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.24mL | 16.22mL | 32.43mL |
| 5mM | 0.65mL | 3.24mL | 6.49mL |
| 10mM | 0.32mL | 1.62mL | 3.24mL |
| 50mM | 0.06mL | 0.32mL | 0.65mL |



