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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Tyrphostin B44, (-) enantiomer/0578/50/50 mg
产品编号:0578/50
市  场 价:¥8380.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>激酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$419.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Tyrphostin B44, (-) enantiomer/0578/50/50 mg
商品介绍
Description:EGFR-kinaseinhibitor
ChemicalName:(R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentinhibitorofepidermalgrowthfactorreceptor(EGFR)kinase(IC50=0.4μM),moreactivethanthe(+)enantiomer(Cat.No.0579).SelectiveoverErbB2.

TechnicalData

M.Wt308.34
FormulaC18H16N2O3
StorageDesiccateat+4°C
CASNumber133550-32-0
PubChemID5328772
InChIKeyUMGQVUWXNOJOSJ-KMHUVPDISA-N
SmilesOC1=C(O)C=CC(C=C(C(N[C@H](C)C2=CC=CC=C2)=O)/C#N)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.2530

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight308.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.24mL16.22mL32.43mL
5mM0.65mL3.24mL6.49mL
10mM0.32mL1.62mL3.24mL
50mM0.06mL0.32mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet