Antiallergicviainhibitionofchemicalmediatorreleasefrommastcells.Showntobeaneffectiveinhibitorofangiogenesis.DemonstratedtoantagonizetheeffectsofangiotensinIIonhumanarteries,possIBLybyaninteractionattheleveloftheAT1receptor.InhibitsTRPV2-mediatedresponses;bindstoAβ40monomersandincreasesAβ40fibrillation.
TranilastisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 327.34 |
Formula | C18H17NO5 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 53902-12-8 |
PubChemID | 5282230 |
InChIKey | NZHGWWWHIYHZNX-CSKARUKUSA-N |
Smiles | COC1=CC=C(C=CC(=O)NC2=CC=CC=C2C(O)=O)C=C1OC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 32.73 | 100 |
Thefollowingdataisbasedontheproductmolecularweight327.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.05mL | 15.27mL | 30.55mL |
5mM | 0.61mL | 3.05mL | 6.11mL |
10mM | 0.31mL | 1.53mL | 3.05mL |
50mM | 0.06mL | 0.31mL | 0.61mL |