Selectivefacilitatorof5-HTuptakeinvitroandinvivo.Hasnoaffinityforawiderangeofreceptors,including5-HTanddopamine(IC50>10μM)andhasnoeffectonnoradrenalinordopamineuptake.Antidepressant,analgesicandneuroprotectivefollowingsystemicadmiNISTrationinvivo.
M.Wt | 458.93 |
Formula | C21H24ClN2NaO4S |
Storage | DesiccateatRT |
Purity | ≥99%(HPLC) |
CASNumber | 30123-17-2 |
PubChemID | 23663953 |
InChIKey | ZLBSUOGMZDXYKE-UHFFFAOYSA-M |
Smiles | [Na+].CN1C2=CC=CC=C2C(NCCCCCCC([O-])=O)C2=CC=C(Cl)C=C2S1(=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.58 | 10 | |
ethanol | 4.58 | 10 | |
water | 45.89 | 100 |
Thefollowingdataisbasedontheproductmolecularweight458.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.18mL | 10.89mL | 21.79mL |
5mM | 0.44mL | 2.18mL | 4.36mL |
10mM | 0.22mL | 1.09mL | 2.18mL |
50mM | 0.04mL | 0.22mL | 0.44mL |