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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Thymosin β4/3390/100U/100 ug
产品编号:3390/100U
市  场 价:¥2580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Thymosin β4/3390/100U/100 ug
商品介绍
Description:Potentactinpolymerizationregulator
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Naturallyoccuring,potentregulatorofactinpolymerizationpresentinhumanplateletsataconcentrationof200-500μM.SequestersG-actinmonomersina1:1ratio(Kd=0.7-1.0μM)andallowsrapidfilamentpolymerizationinthepresenceofprofilin.Implicatedinwoundhealing,inductionofMMPs,chemotaxis,angiogenesis,inflammatoryprocessesandtumorprogression.

TechnicalData

M.Wt4963.49
FormulaC212H350N56O78S
SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES

(Modifications:Ser-1=N-terminalAc)

StorageStoreat-20°C
CASNumber77591-33-4
PubChemID90488838
InChIKeyQBEAMNLSDYIUGM-SIQRNXPUSA-N
SmilesCC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight4963.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.2mL1.01mL2.01mL
5mM0.04mL0.2mL0.4mL
10mM0.02mL0.1mL0.2mL
50mM0mL0.02mL0.04mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet