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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/6-Thioguanine/4061/50/50 mg
产品编号:4061/50
市  场 价:¥900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$45.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/6-Thioguanine/4061/50/50 mg
商品介绍
Description:Anticancerandimmunosuppressiveagent
AlternativeNames:6-TG
ChemicalName:2-Amino-6-mercaptopurine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Anticancerandimmunosuppressiveagentoftenusedtotreatimmunedisordersandleukemia.Displayscytotoxicandantineoplasticproperties;disruptscytosinemethylationbyDNAmethyltransferasesafterincorporationintoDNA.SelectivelykillsBRCA2-defectivetumorsinaxenograftmodel.Alsofacilitatesproteasome-mediateddegradationofDNA(cytosine-5)-methyltransferase1(DNMT1).

TechnicalData

M.Wt167.19
FormulaC5H5N5S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber154-42-7
PubChemID2723601
InChIKeyWYWHKKSPHMUBEB-UHFFFAOYSA-N
SmilesNC1=NC(S)=C2C(NC=N2)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO16.72100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight167.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM5.98mL29.91mL59.81mL
5mM1.2mL5.98mL11.96mL
10mM0.6mL2.99mL5.98mL
50mM0.12mL0.6mL1.2mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet