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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Taxol/1097/10/10 mg
产品编号:1097/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Taxol/1097/10/10 mg
商品介绍
Description:Promotesassemblyandinhibitsdisassemblyofmicrotubules
AlternativeNames:Paclitaxel
ChemicalName:[2aR-[2aα,4β,4aβ,6α,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-hydroxy-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylesterbenzenepropanoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antitumoragent;promotesandstABIlizestubulinpolymerization,causingcellcyclearrest.Inducesautocatalyticactivationofcaspase-10inCCRF-HSB-2cells,triggeringapoptosis.

CompoundLibraries

TaxolisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt853.92
FormulaC47H51NO14
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber33069-62-4
PubChemID441276
InChIKeyRCINICONZNJXQF-VAZQATRQSA-N
SmilesO=C2[C@@]3(C)C([C@@]4(OC(C)=O)[C@H](OC4)C[C@@H]3O)[C@H](OC(C7=CC=CC=C7)=O)[C@@]1(O)[C@](C)(C)C([C@H]2OC(C)=O)=C(C)[C@@H](OC([C@H](O)[C@H]([C@]5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO85.39100mMwithgentlewarming
ethanol21.3525

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight853.92.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.17mL5.86mL11.71mL
5mM0.23mL1.17mL2.34mL
10mM0.12mL0.59mL1.17mL
50mM0.02mL0.12mL0.23mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet