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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TW 37/4038/50/50 mg
产品编号:4038/50
市  场 价:¥19300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$965.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TW 37/4038/50/50 mg
商品介绍
Description:Bcl-2inhibitor;inducesapoptosis
ChemicalName:N-[4-[[2-(1,1-Dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl]benzamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Bcl-2inhibitor(Kivaluesare0.29μMand1.11μMforBcl-2andBcl-XLrespectively).Inhibitstheangiogenicpotentialofendothelialcellsinvitro.InducesS-phasearrestandapoptosisinpancreaticcancercelllines;alsoinhibitstheactivationofNotch-1andJagged-1invitroandinvivo.

TechnicalData

M.Wt573.7
FormulaC33H35NO6S
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber877877-35-5
PubChemID11455910
InChIKeyPQAPVTKIEGUPRN-UHFFFAOYSA-N
SmilesOC1=C(CC2=C(C(C)C)C=CC=C2)C=C(C(NC3=CC=C(S(C4=C(C(C)(C)C)C=CC=C4)(=O)=O)C=C3)=O)C(O)=C1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO57.37100
ethanol2.875

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight573.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.74mL8.72mL17.43mL
5mM0.35mL1.74mL3.49mL
10mM0.17mL0.87mL1.74mL
50mM0.03mL0.17mL0.35mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet