PotentFFA4(GPR120)agonist(pEC50valuesare7.36and7.77forhumanandmouseGPR120respectively).SelectiveforGPR120overfreefattyacidreceptors(pEC50=4.19forFFA1;displaysnoactivityatFFA2orFFA3).Cellpermeable.
SoldunderlicensefromtheUniversityofSouthernDenmark.
TUG891isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 364.41 |
Formula | C23H21FO3 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 1374516-07-0 |
PubChemID | 57522038 |
InChIKey | LPGBXHWIQNZEJB-UHFFFAOYSA-N |
Smiles | FC1=CC(COC2=CC=C(CCC(O)=O)C=C2)=C(C3=CC=C(C)C=C3)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 36.44 | 100 |
Thefollowingdataisbasedontheproductmolecularweight364.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.74mL | 13.72mL | 27.44mL |
5mM | 0.55mL | 2.74mL | 5.49mL |
10mM | 0.27mL | 1.37mL | 2.74mL |
50mM | 0.05mL | 0.27mL | 0.55mL |