PotentcyclophilinAinhibitor(IC50=1.52nM).Approximately27timesmorepotentthancyclosporinA(Cat.No.1101).
TMN355isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 380.8 |
| Formula | C21H14ClFN2O2 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 1186372-20-2 |
| PubChemID | 44249042 |
| InChIKey | SFNLLCUAISZNRV-UHFFFAOYSA-N |
| Smiles | ClC1=C(C(NC(NC2C(C=CC=C4)=C4C3=C2C=CC=C3)=O)=O)C(F)=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 15.23 | 40 |
Thefollowingdataisbasedontheproductmolecularweight380.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.63mL | 13.13mL | 26.26mL |
| 5mM | 0.53mL | 2.63mL | 5.25mL |
| 10mM | 0.26mL | 1.31mL | 2.63mL |
| 50mM | 0.05mL | 0.26mL | 0.53mL |



