VGF-derivedpeptide;spansresidues556-576oftheprecursorsequence.Protectscerebellargranulecells(CGCs)fromserumandpotassiumdeprivation-inducedapoptosis.Increasesenergyexpenditureandpreventsearlyphasediet-induceddiabetes.
M.Wt | 2432.77 |
Formula | C107H170N40O26 |
Sequence | TLQPPASSRRRHFHHALPPAR |
Storage | Desiccateat-20°C |
CASNumber | 869988-94-3 |
PubChemID | 16158480 |
InChIKey | PWWMOXVVMRPYJS-IWCKOKPFSA-N |
Smiles | [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleto1mg/mlinwater |
Thefollowingdataisbasedontheproductmolecularweight2432.77.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.41mL | 2.06mL | 4.11mL |
5mM | 0.08mL | 0.41mL | 0.82mL |
10mM | 0.04mL | 0.21mL | 0.41mL |
50mM | 0.01mL | 0.04mL | 0.08mL |