Selectiveinhibitorofhistonedeacetylase6(HDAC6).InhibitsHCT116growthincombinationwithtaxol(Cat.No.1097).AlsoinhibitsgrowthofMCF-7cellsstimulatedbyestrogen.
TCSHDAC620bisalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 480.7 |
Formula | C26H44N2O4S |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 956154-63-5 |
PubChemID | 23636017 |
InChIKey | DQZMLPMCOMRJOR-MOVGKWKRSA-N |
Smiles | O=C([C@@H](NC(OC(C)(C)C)=O)CCCCCSC(C(C)C)=O)NC1(CC3C2)CC(C3)CC2C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 48.07 | 100 | |
ethanol | 48.07 | 100 |
Thefollowingdataisbasedontheproductmolecularweight480.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.08mL | 10.4mL | 20.8mL |
5mM | 0.42mL | 2.08mL | 4.16mL |
10mM | 0.21mL | 1.04mL | 2.08mL |
50mM | 0.04mL | 0.21mL | 0.42mL |