Selectiveinhibitorofhistonedeacetylase6(HDAC6).InhibitsHCT116growthincombinationwithtaxol(Cat.No.1097).AlsoinhibitsgrowthofMCF-7cellsstimulatedbyestrogen.
TCSHDAC620bisalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 480.7 |
| Formula | C26H44N2O4S |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 956154-63-5 |
| PubChemID | 23636017 |
| InChIKey | DQZMLPMCOMRJOR-MOVGKWKRSA-N |
| Smiles | O=C([C@@H](NC(OC(C)(C)C)=O)CCCCCSC(C(C)C)=O)NC1(CC3C2)CC(C3)CC2C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 48.07 | 100 | |
| ethanol | 48.07 | 100 |
Thefollowingdataisbasedontheproductmolecularweight480.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.08mL | 10.4mL | 20.8mL |
| 5mM | 0.42mL | 2.08mL | 4.16mL |
| 10mM | 0.21mL | 1.04mL | 2.08mL |
| 50mM | 0.04mL | 0.21mL | 0.42mL |



