Integrinverylateantigen-4(VLA-4;α4β1)antagonist(IC50=4.4nM).Blockstheactivationofinflammatorycells.
TCS2314isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 522.59 |
Formula | C28H34N4O6 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 317353-73-4 |
PubChemID | 11226207 |
InChIKey | ITXAAOWFOURIHK-DEOSSOPVSA-N |
Smiles | O=C(N2CCOC[C@H]2[C@@](N3CCC(CC(O)=O)CC3)=O)CC1=CC=C(NC(NC4=C(C)C=CC=C4)=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 52.26 | 100 | |
ethanol | 26.13 | 50 |
Thefollowingdataisbasedontheproductmolecularweight522.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.91mL | 9.57mL | 19.14mL |
5mM | 0.38mL | 1.91mL | 3.83mL |
10mM | 0.19mL | 0.96mL | 1.91mL |
50mM | 0.04mL | 0.19mL | 0.38mL |