SelectivehistonedemethylaseKDM2/7subfamilyinhibitor(IC50valuesare0.2,1.2,6.8,55,83,>100and>120μMforKDM7A,KDM7B,KDM2A,KDM5A,KDM4C,KDM6AandKDM4Arespectively).InhibitsgrowthofHeLaandKYSE-150cancercellsinvitro.
TC-E5002isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 285.38 |
| Formula | C15H27NO4 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1453071-47-0 |
| PubChemID | 71735843 |
| InChIKey | NEHSERYKENINRH-UHFFFAOYSA-N |
| Smiles | O=C(N(CCC(O)=O)O)CCCCCCCCC1CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| 1eq.NaOH | 28.54 | 100 | |
| DMSO | 28.54 | 100 |
Thefollowingdataisbasedontheproductmolecularweight285.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.5mL | 17.52mL | 35.04mL |
| 5mM | 0.7mL | 3.5mL | 7.01mL |
| 10mM | 0.35mL | 1.75mL | 3.5mL |
| 50mM | 0.07mL | 0.35mL | 0.7mL |



