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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TC OT 39/4625/10/10 mg
产品编号:4625/10
市  场 价:¥4900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$245.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TC OT 39/4625/10/10 mg
商品介绍
Description:Potentnon-peptideoxytocinreceptorpartialagoNIST;alsoV1areceptorantagonist
ChemicalName:(2S)-N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-2-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)thioxomethyl]-1-pyrrolidinecarboxamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentnon-peptideoxytocinreceptorpartialagonist(EC50valuesare33nMand850nMfortheoxytocinreceptorandV2vasopressinreceptorrespectively).AlsoaV1avasopressinreceptorantagonist(Ki=330nM).Activeinvivoinaratmodelofuterineresponse.

CompoundLibraries

TCOT39isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt600.78
FormulaC32H40N8O2S
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber479232-57-0
PubChemID24776341
InChIKeyPAEBEUZTAPIOIO-UHFFFAOYSA-N
SmilesO=C(N5[C@H]([C@](N6CCN(C)CCC6)=S)CCC5)NCC(C(C)=C2)=CC=C2C(N1C(C=CC=C3)=C3NC(N(C)N=C4)=C4C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto100mMin1eq.HClandto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight600.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.66mL8.32mL16.65mL
5mM0.33mL1.66mL3.33mL
10mM0.17mL0.83mL1.66mL
50mM0.03mL0.17mL0.33mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet