Potentnon-peptideoxytocinreceptorpartialagonist(EC50valuesare33nMand850nMfortheoxytocinreceptorandV2vasopressinreceptorrespectively).AlsoaV1avasopressinreceptorantagonist(Ki=330nM).Activeinvivoinaratmodelofuterineresponse.
TCOT39isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 600.78 |
Formula | C32H40N8O2S |
Storage | Storeat-20°C |
Purity | ≥97%(HPLC) |
CASNumber | 479232-57-0 |
PubChemID | 24776341 |
InChIKey | PAEBEUZTAPIOIO-UHFFFAOYSA-N |
Smiles | O=C(N5[C@H]([C@](N6CCN(C)CCC6)=S)CCC5)NCC(C(C)=C2)=CC=C2C(N1C(C=CC=C3)=C3NC(N(C)N=C4)=C4C1)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleto100mMin1eq.HClandto100mMinDMSO |
Thefollowingdataisbasedontheproductmolecularweight600.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.66mL | 8.32mL | 16.65mL |
5mM | 0.33mL | 1.66mL | 3.33mL |
10mM | 0.17mL | 0.83mL | 1.66mL |
50mM | 0.03mL | 0.17mL | 0.33mL |