InhibitorofSir2p(IC50=60μM),anNAD+-dependentSir2familydeacetylaserequiredforchromatin-dependentsilencinginyeast.
SplitomicinisalsoofferedaspartoftheTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 198.22 |
Formula | C13H10O2 |
Storage | Storeat-20°C |
Purity | ≥97%(HPLC) |
CASNumber | 5690-03-9 |
PubChemID | 5269 |
InChIKey | ISFPDBUKMJDAJH-UHFFFAOYSA-N |
Smiles | O=C1CCC2=C(O1)C=CC1=CC=CC=C21 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 19.82 | 100 | |
ethanol | 19.82 | 100 |
Thefollowingdataisbasedontheproductmolecularweight198.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 5.04mL | 25.22mL | 50.45mL |
5mM | 1.01mL | 5.04mL | 10.09mL |
10mM | 0.5mL | 2.52mL | 5.04mL |
50mM | 0.1mL | 0.5mL | 1.01mL |