请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Sildenafil citrate/3784/50/50 mg
产品编号:3784/50
市  场 价:¥13300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$665.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Sildenafil citrate/3784/50/50 mg
商品介绍
Description:Orallyactive,potentPDE5inhibitor
ChemicalName:1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazinecitrate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactive,potentinhibitorofphosphodiesterase5(PDE5)(IC50=4nM).Enhancesnitricoxide-dependentrelaxationofhumancorpuscavernosuminvitro.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

SildenafilcitrateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt666.7
FormulaC22H30N6O4S.C6H8O7
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber171599-83-0
PubChemID62853
InChIKeyDEIYFTQMQPDXOT-UHFFFAOYSA-N
SmilesO=C(O)C(O)(CC(O)=O)CC(O)=O.CN1CCN(S(C2=CC=C(OCC)C(C(NC4=C3N(C)N=C4CCC)=NC3=O)=C2)(=O)=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO66.67100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight666.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.5mL7.5mL15mL
5mM0.3mL1.5mL3mL
10mM0.15mL0.75mL1.5mL
50mM0.03mL0.15mL0.3mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet