Estrogenreceptor(ER)αinhibitor.Inhibitsproliferationofdrug-resistantERα-positivebreastandovariancancercells.Inducessustainedactivationoftheunfoldedproteinresponse.Activeinvivo.
M.Wt | 331.36 |
Formula | C21H17NO3 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 56632-39-4 |
PubChemID | 3860640 |
InChIKey | FABLAHMQSQFDHR-UHFFFAOYSA-N |
Smiles | CC1=CC=CC2=C1NC(C2(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 33.14 | 100 | |
ethanol | 33.14 | 100 |
Thefollowingdataisbasedontheproductmolecularweight331.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.02mL | 15.09mL | 30.18mL |
5mM | 0.6mL | 3.02mL | 6.04mL |
10mM | 0.3mL | 1.51mL | 3.02mL |
50mM | 0.06mL | 0.3mL | 0.6mL |