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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SR 9243/6138/50/50 mg
产品编号:6138/50
市  场 价:¥12580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$629.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SR 9243/6138/50/50 mg
商品介绍
Description:SelectiveLXRinverseagoNIST
ChemicalName:N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]benzenesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveLXRinverseagonist.Exhibitsnosignificantactivityatothernuclearreceptorsatmaximallyeffectiveconcentration.InhibitstheWarburgeffectandlipogenesisbydown-regulationofLXR-mediatedgeneexpression.SelectivelyreducescellviABIlityandinducesapoptosisincancercelllinesinvitro.Suppresseshepaticsteatosisandinhibitsgrowthoftumorxenograftsinmice.

TechnicalData

M.Wt626.62
FormulaC31H32BrNO4S2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1613028-81-1
PubChemID76073169
InChIKeyFYQFEJFTCLKXTQ-UHFFFAOYSA-N
SmilesCC1=CC(C)=CC(C)=C1S(N(CCC2=CC=CC(Br)=C2)CC(C=C3)=CC=C3C4=CC(S(=O)(C)=O)=CC=C4)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO12.5320

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight626.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.6mL7.98mL15.96mL
5mM0.32mL1.6mL3.19mL
10mM0.16mL0.8mL1.6mL
50mM0.03mL0.16mL0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet