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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SR 9009/5855/10/10 mg
产品编号:5855/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SR 9009/5855/10/10 mg
商品介绍
Description:Rev-Erbα/βagoNIST
ChemicalName:Ethyl3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Rev-Erbα/βagonist(EC50=710nM;Kd=800nM).AlterscircADIanlocomotoractivityandcoreclockhypothalamicgeneexpressioninmice.Inducesweightlossindiet-inducedobesemice.Brainpenetrant.

TechnicalData

M.Wt437.94
FormulaC20H24ClN3O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1379686-30-2
PubChemID57394020
InChIKeyMMJJNHOIVCGAAP-UHFFFAOYSA-N
SmilesClC(C=C1)=CC=C1CN(CC2CCN(C(OCC)=O)C2)CC3=CC=C([N+]([O-])=O)S3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.79100
ethanol43.79100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight437.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.28mL11.42mL22.83mL
5mM0.46mL2.28mL4.57mL
10mM0.23mL1.14mL2.28mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet