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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SR 1078/4874/10/10 mg
产品编号:4874/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SR 1078/4874/10/10 mg
商品介绍
Description:RORα/γagoNIST
ChemicalName:N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Agonistofretinoicacidreceptor-relatedorphanreceptors(ROR)RORα/γ.IncreasestranscriptionofRORαtargetgenes;thoughttoincreasep53stABIlity.

LicensingInformation

SoldunderlicensefromTheScrippsResearchInstitute.

CompoundLibraries

SR1078isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt431.25
FormulaC17H10F9NO2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1246525-60-9
PubChemID17980288
InChIKeyDUXWIYXHHGNUJU-UHFFFAOYSA-N
SmilesOC(C(F)(F)F)(C(F)(F)F)C(C=C1)=CC=C1NC(C2=CC=C(C(F)(F)F)C=C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.12100
ethanol43.12100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight431.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.32mL11.59mL23.19mL
5mM0.46mL2.32mL4.64mL
10mM0.23mL1.16mL2.32mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet