Agonistofretinoicacidreceptor-relatedorphanreceptors(ROR)RORα/γ.IncreasestranscriptionofRORαtargetgenes;thoughttoincreasep53stABIlity.
SoldunderlicensefromTheScrippsResearchInstitute.
SR1078isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 431.25 |
Formula | C17H10F9NO2 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 1246525-60-9 |
PubChemID | 17980288 |
InChIKey | DUXWIYXHHGNUJU-UHFFFAOYSA-N |
Smiles | OC(C(F)(F)F)(C(F)(F)F)C(C=C1)=CC=C1NC(C2=CC=C(C(F)(F)F)C=C2)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 43.12 | 100 | |
ethanol | 43.12 | 100 |
Thefollowingdataisbasedontheproductmolecularweight431.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.32mL | 11.59mL | 23.19mL |
5mM | 0.46mL | 2.32mL | 4.64mL |
10mM | 0.23mL | 1.16mL | 2.32mL |
50mM | 0.05mL | 0.23mL | 0.46mL |