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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SMANT hydrochloride/4662/50/50 mg
产品编号:4662/50
市  场 价:¥11700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$585.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SMANT hydrochloride/4662/50/50 mg
商品介绍
Description:InhibitsSmoothened(Smo)accumulation
ChemicalName:N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamidehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofSmoothened(Smo)signalingviaauniquemechanism.InhibitsShh-inducedaccumulationofSmo::EGFPfusionproteinintheprimarycilium(IC50=1.1μM).Inhibitsbothwild-typeSmoandanoncogenicform(SmoM2)withsimilarefficacy.

TechnicalData

M.Wt375.73
FormulaC16H23BrN2O.HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber1177600-74-6
PubChemID2900213
InChIKeyXQESCHFXROUCOQ-UHFFFAOYSA-N
SmilesBrC1=CC=C(NC(CCN2CC(C)CC(C)C2)=O)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.57100
ethanol7.5120
water7.5120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight375.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.66mL13.31mL26.61mL
5mM0.53mL2.66mL5.32mL
10mM0.27mL1.33mL2.66mL
50mM0.05mL0.27mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet