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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SLV 320/3344/10/10 mg
产品编号:3344/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SLV 320/3344/10/10 mg
商品介绍
Description:PotentandselectiveA1antagoNIST
ChemicalName:trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveadenosineA1receptorantagonist(Kivaluesare1,200,398and3981nMathumanA1,A3,A2AandA2Breceptorsrespectively).Suppressescardiacfibrosisandattenuatesalbuminuria,withouteffectonbloodpressureinanimalmodelsofchronicrenalfailure.Orallyactive.

TechnicalData

M.Wt308.38
FormulaC18H20N4O
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber251945-92-3
PubChemID9953065
InChIKeyRBZNJGHIKXAKQE-UHFFFAOYSA-N
SmilesO[C@@H](CC4)CC[C@H]4NC1=C2C(NC=C2)=NC(C3=CC=CC=C3)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.84100
ethanol15.4250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight308.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.24mL16.21mL32.43mL
5mM0.65mL3.24mL6.49mL
10mM0.32mL1.62mL3.24mL
50mM0.06mL0.32mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet