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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SID 7969543/3440/50/50 mg
产品编号:3440/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SID 7969543/3440/50/50 mg
商品介绍
Description:Selectivesteroidogenicfactor-1(SF-1,NR5A1)inhibitor
ChemicalName:Ethyl2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivesteroidogenicfactor-1(SF-1,NR5A1)inhibitor(IC50valuesare0.76,>33and>33μMatSF-1,RORαandVP16respectively).InhibitsSF-1-dependentluciferaseexpressioninHEK293Tcellsinvitro(IC50=30nM).

CompoundLibraries

SID7969543isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt452.46
FormulaC24H24N2O7
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber868224-64-0
PubChemID4076092
InChIKeyKWMBIIQCLUIHDI-UHFFFAOYSA-N
SmilesO=C2C1=CC=CC(OC(C)C(OCC)=O)=C1C=CN2CC(NC3=CC=C(OCCO4)C4=C3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.25100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight452.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.21mL11.05mL22.1mL
5mM0.44mL2.21mL4.42mL
10mM0.22mL1.11mL2.21mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet