Selectivesteroidogenicfactor-1(SF-1,NR5A1)inhibitor(IC50valuesare0.76,>33and>33μMatSF-1,RORαandVP16respectively).InhibitsSF-1-dependentluciferaseexpressioninHEK293Tcellsinvitro(IC50=30nM).
SID7969543isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 452.46 |
Formula | C24H24N2O7 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 868224-64-0 |
PubChemID | 4076092 |
InChIKey | KWMBIIQCLUIHDI-UHFFFAOYSA-N |
Smiles | O=C2C1=CC=CC(OC(C)C(OCC)=O)=C1C=CN2CC(NC3=CC=C(OCCO4)C4=C3)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 45.25 | 100 |
Thefollowingdataisbasedontheproductmolecularweight452.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.21mL | 11.05mL | 22.1mL |
5mM | 0.44mL | 2.21mL | 4.42mL |
10mM | 0.22mL | 1.11mL | 2.21mL |
50mM | 0.04mL | 0.22mL | 0.44mL |