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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SI-2 hydrochloride/5964/10/10 mg
产品编号:5964/10
市  场 价:¥3300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$165.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SI-2 hydrochloride/5964/10/10 mg
商品介绍
Description:Steroidreceptorcoactivator3(SRC-3)inhibitor
ChemicalName:1-(2-Pyridinyl)ethanone2-(1-methyl-1H-benzimidazol-2-yl)hydrazonehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentsteroidreceptorcoactivator3(SRC-3)inhibitor.ReducesSRC1,SRC2andSRC3levelsinbreastcancercelllines.Inhibitscellgrowth(IC50=3.4nM),inducesapoptosisandattenuatesmigrationofMDA-MB48breastcancercellsinvitro.InhibitstumorgrowthinaMDA-MB48cellbreastcancermousemodel.Orallyavailable.

TechnicalData

M.Wt301.78
FormulaC15H15N5.HCl
StorageStoreat+4°C
Purity≥98%(HPLC)
PubChemID121513909
InChIKeyCDYJHORKRVKALB-NWBUNABESA-N
SmilesCN1C(N/N=C(C2=CC=CC=N2)C)=NC3=CC=CC=C13.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO6.0420
water15.0950

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight301.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.31mL16.57mL33.14mL
5mM0.66mL3.31mL6.63mL
10mM0.33mL1.66mL3.31mL
50mM0.07mL0.33mL0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet