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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SEW 2871/2284/10/10 mg
产品编号:2284/10
市  场 价:¥1580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$79.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SEW 2871/2284/10/10 mg
商品介绍
Description:Cell-permeable,selectiveS1P1receptoragoNIST
ChemicalName:5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]1,2,4-oxADIazole
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Novel,potentandselectivesphingosine-1-phosphate1(S1P1)receptoragonist.ActivatesS1P1receptorwithanEC50of13nM,butdoesnotactivateS1P2,S1P3,S1P4orS1P5receptorsatconcentrationsupto10μM.Cell-permeableandactiveinvivo.

TechnicalData

M.Wt440.36
FormulaC20H10F6N2OS
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber256414-75-2
PubChemID4077460
InChIKeyOYMNPJXKQVTQTR-UHFFFAOYSA-N
SmilesFC(F)(F)C1=C(C=C(S1)C1=NC(=NO1)C1=CC(=CC=C1)C(F)(F)F)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.8120
ethanol8.8120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight440.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.35mL22.71mL
5mM0.45mL2.27mL4.54mL
10mM0.23mL1.14mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet