PotentandselectiveA1adenosinereceptoragonist(Kivaluesare23,>10000and25000nMforA1,A2AandA2Breceptorsrespectively).Causesasustainedfallinbloodpressureandheartrateinspontaneoushypertensiveratsandinhibitsadenosinedeaminase-stimulatedlipolysisinratADIpocytes(Ki=8nM).
SDZWAG994isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 363.41 |
Formula | C17H25N5O4 |
Storage | Desiccateat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 130714-47-5 |
PubChemID | 164305 |
InChIKey | JAKAFSGZUXCHLF-LSCFUAHRSA-N |
Smiles | O[C@@H]1[C@@H](CO)O[C@@H](N(C=N4)C2=C4C(NC3CCCCC3)=NC=N2)[C@@H]1OC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
1.1eq.NaOH | 36.34 | 100 | |
DMSO | 36.34 | 100 | |
ethanol | 36.34 | 100 |
Thefollowingdataisbasedontheproductmolecularweight363.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.75mL | 13.76mL | 27.52mL |
5mM | 0.55mL | 2.75mL | 5.5mL |
10mM | 0.28mL | 1.38mL | 2.75mL |
50mM | 0.06mL | 0.28mL | 0.55mL |