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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SC 26196/4189/50/50 mg
产品编号:4189/50
市  场 价:¥13300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$665.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SC 26196/4189/50/50 mg
商品介绍
Description:SelectiveΔ6desaturaseinhibitor
ChemicalName:α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataDatasheetsReferences

BiologicalActivity

SelectiveΔ6desaturaseinhibitor(IC50=0.2μMinvitro).DisplaysselectivityoverΔ5andΔ9desaturases(IC50valuesare>200μMinvitro).Exhibitsanti-inflammatorypropertiesinamouseedemamodel.EliminatesCSCsfromovariancancercelllinesandinhibitssphereformationinvitro.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt423.55
FormulaC27H29N5
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber218136-59-5
PubChemID9845201
InChIKeyQFYKXKMYVYOUNJ-JBASAIQMSA-N
SmilesN#CC(C3=CC=CC=C3)(C4=CC=CC=C4)CCCN1CCN(/N=C/C2=CN=CC=C2)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight423.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.36mL11.8mL23.61mL
5mM0.47mL2.36mL4.72mL
10mM0.24mL1.18mL2.36mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet