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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SB 505124/3263/50/50 mg
产品编号:3263/50
市  场 价:¥18500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$925.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SB 505124/3263/50/50 mg
商品介绍
Description:SelectiveinhibitorofTGF-βRI,ALK4andALK7
ChemicalName:2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitoroftransforminggrowthfactor-βtypeIreceptor(ALK5),ALK4andALK7(IC50valuesare47and129nMforALK5andALK4respectively).SelectivelyinhibitssignalingfromTGF-βandactivin;doesnotinhibitotherALKfamilymembers.

TechnicalData

M.Wt335.4
FormulaC20H21N3O2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber694433-59-5
PubChemID9858940
InChIKeyWGZOTBUYUFBEPZ-UHFFFAOYSA-N
SmilesCC(C)(C)C1=NC(C2=CC(OCO4)=C4C=C2)=C(C3=NC(C)=CC=C3)N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl33.54100
DMSO33.54100
ethanol8.3825

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight335.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.98mL14.91mL29.82mL
5mM0.6mL2.98mL5.96mL
10mM0.3mL1.49mL2.98mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet