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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SB 332235/5671/10/10 mg
产品编号:5671/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SB 332235/5671/10/10 mg
商品介绍
Description:PotentCXCR2antagoNIST
ChemicalName:6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentCXCR2antagonist(IC50=7.7nM).Exhibits285-foldselectivityforCXCR2overCXCR1.Reducesleukocytenumbersinsynovialfluidinacuteandchronicrabbitarthritismodels.Alsoreducessynovialfluideicosanoidandcytokinelevelsinarabbitchronicarthritismodel.InhibitsproliferationofAMLcelllinesinvitro.

TechnicalData

M.Wt410.66
FormulaC13H10Cl3N3O4S
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber276702-15-9
PubChemID9887803
InChIKeyWTLRWOHEKQGKDS-UHFFFAOYSA-N
SmilesClC1=C(S(=O)(N)=O)C(O)=C(NC(NC2=C(Cl)C(Cl)=CC=C2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.07100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight410.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.44mL12.18mL24.35mL
5mM0.49mL2.44mL4.87mL
10mM0.24mL1.22mL2.44mL
50mM0.05mL0.24mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet