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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SB 265610/2724/50/50 mg
产品编号:2724/50
市  场 价:¥16500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$825.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SB 265610/2724/50/50 mg
商品介绍
Description:PotentCXCR2antagoNIST
ChemicalName:N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentCXCR2antagonistthatinhibitsCINC-1-mediatedbutnotC5a-mediatedCa2+mobilization(IC50valuesare3.4and6800nMrespectively).InhibitsCINC-inducedchemotaxisandattenuatesneutrophilaccumulationininflammatorylunginjuryinvivo.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline

TechnicalData

M.Wt357.16
FormulaC14H9BrN6O
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber211096-49-0
PubChemID9841667
InChIKeySEDUMQWZEOMXSO-UHFFFAOYSA-N
SmilesO=C(NC3=C(Br)C=CC=C3)NC1=CC=C(C#N)C2=C1NN=N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.72100
ethanol3.5710

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight357.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.8mL14mL28mL
5mM0.56mL2.8mL5.6mL
10mM0.28mL1.4mL2.8mL
50mM0.06mL0.28mL0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet