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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SAG 21k/5282/10/10 mg
产品编号:5282/10
市  场 价:¥4980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$249.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SAG 21k/5282/10/10 mg
商品介绍
Description:Hedgehogsignalingactivator;brainpenetrantandorallybioavailable
ChemicalName:3-Chloro-4,7-difluoro-N-[[2-methoxy-5-(4-pyridinyl)phenyl]methyl]-N-trans-4-(methylamino)cyclohexyl]benzo[b]thiophene-2-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentHedgehogsignalingactivator(EC50=0.4nM).Orallybioavailableandbrainpenetrant.

TechnicalData

M.Wt556.07
FormulaC29H28ClF2N3O2S
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber946002-48-8
PubChemID16678532
InChIKeyYVIFQUJDZSAFKG-UHFFFAOYSA-N
SmilesCOC1=C(CN([C@@H]2CC[C@@H](NC)CC2)C(C3=C(Cl)C4=C(C(F)=CC=C4F)S3)=O)C=C(C5=CC=NC=C5)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO55.61100
ethanol11.1220

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight556.07.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.8mL8.99mL17.98mL
5mM0.36mL1.8mL3.6mL
10mM0.18mL0.9mL1.8mL
50mM0.04mL0.18mL0.36mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet