PotentHedgehogsignalingactivator(EC50=0.4nM).Orallybioavailableandbrainpenetrant.
M.Wt | 556.07 |
Formula | C29H28ClF2N3O2S |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 946002-48-8 |
PubChemID | 16678532 |
InChIKey | YVIFQUJDZSAFKG-UHFFFAOYSA-N |
Smiles | COC1=C(CN([C@@H]2CC[C@@H](NC)CC2)C(C3=C(Cl)C4=C(C(F)=CC=C4F)S3)=O)C=C(C5=CC=NC=C5)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 55.61 | 100 | |
ethanol | 11.12 | 20 |
Thefollowingdataisbasedontheproductmolecularweight556.07.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.8mL | 8.99mL | 17.98mL |
5mM | 0.36mL | 1.8mL | 3.6mL |
10mM | 0.18mL | 0.9mL | 1.8mL |
50mM | 0.04mL | 0.18mL | 0.36mL |