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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SA 4503 dihydrochloride/4951/10/10 mg
产品编号:4951/10
市  场 价:¥3300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$165.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SA 4503 dihydrochloride/4951/10/10 mg
商品介绍
Description:Selectiveσ1receptoragoNIST
ChemicalName:1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-piperazinedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveσ1receptoragonist(IC50=17.4nM).Exhibitsselectivityforσ1overσ2receptors.InhibitsangiotensinII-inducedcardiomyocytehypertrophyinvitroandattenuatesmyocardialhypertrophyinvivo.Enhancesbrainplasticityandsensorimotorfunctioninaratmodelofexperimentalstroke.

CompoundLibraries

SA4503dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt441.43
FormulaC23H32N2O2.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber165377-44-6
PubChemID9954941
InChIKeyXWOXAKBQEMQMFH-UHFFFAOYSA-N
SmilesCOC1=C(OC)C=CC(CCN2CCN(CCCC3=CC=CC=C3)CC2)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.8320
water44.14100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.33mL22.65mL
5mM0.45mL2.27mL4.53mL
10mM0.23mL1.13mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet