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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/S4/5577/50/50 mg
产品编号:5577/50
市  场 价:¥9180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$459.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/S4/5577/50/50 mg
商品介绍
Description:HighaffinityandselectiveCAIXandCAXIIinhibitor
ChemicalName:4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenylsulfamate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityandselectiveCAIXandCAXIIinhibitor(Kivaluesare2,7,547and5600nMforCAXII,IX,IIandI,respectively).Inhibitsmigrationandproliferationofbreastcancercellsinvitro.Inhibitslungmetastasisinmicebearingbreasttumorxenografts,withoutaffectingprimarytumor.

CompoundLibraries

S4isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt335.38
FormulaC15H17N3O4S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1330061-67-0
PubChemID53342705
InChIKeyHGVHSNXRZYOTPD-UHFFFAOYSA-N
SmilesNS(OC1=CC=C(NC(NC2=CC(C)=CC(C)=C2)=O)C=C1)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.54100
ethanol6.7120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight335.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.98mL14.91mL29.82mL
5mM0.6mL2.98mL5.96mL
10mM0.3mL1.49mL2.98mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet