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主营：分子类，蛋白类，抗体类，生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/S26948/3690/10/10 mg
产品编号：3690/10
市  场 价：¥3980.00
场      地：美国(厂家直采)
产品分类： 生化试剂>生物分子>受体>
联系QQ：1570468124
电话号码：4000-520-616
邮      箱： info@ebiomall.com
美  元  价：$199.00
品      牌： Tocris
公      司：Tocris Bioscience
公司分类：
Tocris/S26948/3690/10/10 mg
商品介绍
Description:SelectivePPARγagoNIST;antidiabeticagent
ChemicalName:[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivePPARγagonist(EC50=8.83nM).DrivesnormalADIpocytedifferentiationandexhibitsalipid-loweringeffect;reducesatherosclerosisinE2-KImice.Displaysantidiabeticpropertiesandimproveshepaticinsulinsensitivityinintralipid-infusion(IL)rats.

CompoundLibraries

S26948isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt519.57
FormulaC28H25NO7S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber353280-43-0
PubChemID9958279
InChIKeyNSMJEHGOMXSLCW-UHFFFAOYSA-N
SmilesO=C(C3=CC=CC=C3)C1=CC=C(N(CCOC4=CC=C(CC(C(OC)=O)C(OC)=O)C=C4)C(S2)=O)C2=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO51.96100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight519.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.92mL9.62mL19.25mL
5mM0.38mL1.92mL3.85mL
10mM0.19mL0.96mL1.92mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet