SelectivePPARγagonist(EC50=8.83nM).DrivesnormalADIpocytedifferentiationandexhibitsalipid-loweringeffect;reducesatherosclerosisinE2-KImice.Displaysantidiabeticpropertiesandimproveshepaticinsulinsensitivityinintralipid-infusion(IL)rats.
S26948isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 519.57 |
| Formula | C28H25NO7S |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 353280-43-0 |
| PubChemID | 9958279 |
| InChIKey | NSMJEHGOMXSLCW-UHFFFAOYSA-N |
| Smiles | O=C(C3=CC=CC=C3)C1=CC=C(N(CCOC4=CC=C(CC(C(OC)=O)C(OC)=O)C=C4)C(S2)=O)C2=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 51.96 | 100 |
Thefollowingdataisbasedontheproductmolecularweight519.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.92mL | 9.62mL | 19.25mL |
| 5mM | 0.38mL | 1.92mL | 3.85mL |
| 10mM | 0.19mL | 0.96mL | 1.92mL |
| 50mM | 0.04mL | 0.19mL | 0.38mL |



