LSD1inhibitor(IC50=990nM;Ki=610nM).ExhibitsselectivityforLSD1overMAO-BandMAO-A(Kivaluesare17and110μM,respectively).
| M.Wt | 311.75 |
| Formula | C16H15F2NO.HCl |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1239262-36-2 |
| PubChemID | 121513887 |
| InChIKey | CTSUZAFTJVLOIX-SBKWZQTDSA-N |
| Smiles | FC1=CC([C@@H]2C[C@H]2N)=C(OCC3=CC=CC=C3)C(F)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.18 | 100 | |
| water | 15.59 | 50 |
Thefollowingdataisbasedontheproductmolecularweight311.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.21mL | 16.04mL | 32.08mL |
| 5mM | 0.64mL | 3.21mL | 6.42mL |
| 10mM | 0.32mL | 1.6mL | 3.21mL |
| 50mM | 0.06mL | 0.32mL | 0.64mL |



