Inverseagonistoftheconstitutiveandrostanereceptor(CAR).InhibitsCARactivityviarecruitmentofnuclearreceptorco-repressor(NCoR).SuppressesCITCO-inducedCYP2B6geneexpressioninhumanprimaryhepatocytes.
S07662isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 300.38 |
| Formula | C16H16N2O2S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 883226-64-0 |
| PubChemID | 2732040 |
| InChIKey | UITFWLJMEZPXOF-UHFFFAOYSA-N |
| Smiles | CC2=C(CNC(NCC3=CC=CS3)=O)C1=CC=CC=C1O2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 30.04 | 100 | |
| ethanol | 15.02 | 50 |
Thefollowingdataisbasedontheproductmolecularweight300.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.33mL | 16.65mL | 33.29mL |
| 5mM | 0.67mL | 3.33mL | 6.66mL |
| 10mM | 0.33mL | 1.66mL | 3.33mL |
| 50mM | 0.07mL | 0.33mL | 0.67mL |



