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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Rosiglitazone/5325/50/50 mg
产品编号:5325/50
市  场 价:¥5900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$295.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Rosiglitazone/5325/50/50 mg
商品介绍
Description:PotentandselectivePPARγagoNIST;antidiabeticagent.
AlternativeNames:BRL49653
ChemicalName:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivePPARγagonist(EC50=60nM);exhibitsnoactivityatPPARαandPPARβ.PromotesdifferentiationofpluripotentC3H10T1/2stemcellsintoADIpocytes.Exhibitsantihyperglycemicactivityindiabeticob/obmousemodel.Antidiabeticagent.

CompoundLibraries

RosiglitazoneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt357.43
FormulaC18H19N3O3S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber122320-73-4
PubChemID77999
InChIKeyYASAKCUCGLMORW-UHFFFAOYSA-N
SmilesCN(CCOC1=CC=C(CC2SC(NC2=O)=O)C=C1)C3=CC=CC=N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl35.74100
DMSO35.74100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight357.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.8mL13.99mL27.98mL
5mM0.56mL2.8mL5.6mL
10mM0.28mL1.4mL2.8mL
50mM0.06mL0.28mL0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet