MoreactiveenantiomerofthePDE4inhibitorrolipram(Cat.No.0905);2-10-foldmorepotentthantheS-(+)enantiomer(Cat.No.1350).AlsoavailableaspartofthePhosphodiesteraseInhibitorTocriset™.
(R)-(-)-RolipramisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 275.35 |
| Formula | C16H21NO3 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 85416-75-7 |
| PubChemID | 448055 |
| InChIKey | HJORMJIFDVBMOB-LBPRGKRZSA-N |
| Smiles | O=C1NC[C@@H](C2=CC(OC3CCCC3)=C(OC)C=C2)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.54 | 100 | |
| ethanol | 27.54 | 100 |
Thefollowingdataisbasedontheproductmolecularweight275.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.63mL | 18.16mL | 36.32mL |
| 5mM | 0.73mL | 3.63mL | 7.26mL |
| 10mM | 0.36mL | 1.82mL | 3.63mL |
| 50mM | 0.07mL | 0.36mL | 0.73mL |



